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Product Name
CA1 antibody
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Description
CA1 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, mouse spleen tissue, rat spleen tissue. Positive IP detected in K-562 cells. Positive IHC detected in human tonsillitis tissue. Observed molecular weight by Western-blot: 29 kDa
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Tested applications
ELISA, WB, IP, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CA I antibody; CA1 antibody; CAB antibody; Car1 antibody; Carbonate dehydratase I antibody; Carbonic anhydrase 1 antibody; Carbonic anhydrase B antibody; carbonic anhydrase I antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CA1 recombinant protein (Accession Number: NM_001164830). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:50-1:500
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:108741(CA1 antibody) at dilution of 1:500
IP Result of anti-CA1 (IP:Catalog No:108741, 4ug; Detection:Catalog No:108741 1:500) with K-562 cells lysate 1200ug.
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Background
CA1(Carbonic anhydrase 1) is also named as CAB and belongs to the alpha-carbonic anhydrase family, which may reside in cytoplasm, in mitochondria, or in secretory granules, or associate with membranes in cell. It forms a large family of genes encoding zinc metalloenzymes of great physiologic importance. Extracellular CA1 mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation(PMID:17259996).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"