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Product Name
C4 (alpha chain) antibody
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Description
C4 (alpha chain) Rabbit Polyclonal antibody. Positive WB detected in human blood tissue. Observed molecular weight by Western-blot: 95 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
Acidic complement C4 antibody; C4A antibody; C4A2 antibody; C4A3 antibody; C4A4 antibody; C4A6 antibody; C4S antibody; CO4 antibody; Complement C4 A antibody; CPAMD2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of C4 (alpha chain) recombinant protein (Accession Number: NM_007293). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
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Validations
human blood tissue were subjected to SDS PAGE followed by western blot with Catalog No:108727(C4A Antibody) at dilution of 1:3000
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Background
Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor and the alpha chain. This antibody raised against 1017-1336aa of human C4A protein recognize C4A alpha chain.
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