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Product Name
C1R antibody
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Description
C1R Rabbit Polyclonal antibody. Positive WB detected in human blood tissue. Observed molecular weight by Western-blot: 85 kDa, 30 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
C1R antibody; Complement C1r subcomponent antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of C1R recombinant protein (Accession Number: NM_001733). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human blood tissue were subjected to SDS PAGE followed by western blot with Catalog No:108689(C1R Antibody) at dilution of 1:1000
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Background
The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full-length C1r chain and the cleaved B chain.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"