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Product Name
C1QA antibody
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Description
C1QA Rabbit Polyclonal antibody. Positive IP detected in mouse liver tissue. Positive WB detected in human spleen tissue, human colon tissue, human heart tissue, human liver tissue, human lung tissue, mouse liver tissue, mouse serum tissue. Observed molecular weight by Western-blot: 30 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
C1QA antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of C1QA recombinant protein (Accession Number: NM_015991). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:1000
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Validations
human spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:108685(C1QA antibody) at dilution of 1:500
IP Result of anti-C1QA (IP:Catalog No:108685, 4ug; Detection:Catalog No:108685 1:300) with mouse liver tissue lysate 4000ug.
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Background
The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. This antibody is raised against C1QA which is the A-chain polypeptide of human complement subcomponent C1q.
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References
- Boulay AC, Mazeraud A, Cisternino S. Immune quiescence of the brain is set by astroglial connexin 43. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(10):4427-39. 2015.
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