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Product Name
BTG2 antibody
- Documents
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Description
BTG2 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human small intestine tissue, human kidney tissue.
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
BTG family member 2 antibody; BTG family antibody; member 2 antibody; BTG2 antibody; PC3 antibody; Protein BTG2 antibody; TIS21 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of BTG2 recombinant protein (Accession Number: NM_006763). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Immunohistochemistry of paraffin-embedded human small intestine slide using Catalog No:108542(BTG2 Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human small intestine slide using Catalog No:108542(BTG2 Antibody) at dilution of 1:50
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108542(BTG2 Antibody) at dilution of 1:1000
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Background
Protein BTG2, the anti-proliferative human homolog of murine Pc3/Tis21, belongs to the BTG/Tob family. This family has structurally related proteins that appear to have anti-proliferative properties. It has been demonstrated that BTG2 is p53-inducible and is involved in cell cycle control and cellular response to DNA damage (PMID: 8944033). As a transcriptional co-regulator, BTG2 has been shown to interact with CAF1 and POP2, and works as a co-activator of ERa-mediated transcription via a CCR4-like complex (PMID: 18974182).
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