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Product Name
BRD8 antibody
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Description
BRD8 Mouse Monoclonal antibody. Positive WB detected in fetal human brain tissue. Observed molecular weight by Western-blot: 120 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
BRD8 antibody; bromodomain containing 8 antibody; p120 antibody; SMAP antibody; SMAP2 antibody; TrCP120 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of BRD8 recombinant protein (Accession Number: BC008039). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
fetal human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:107022(BRD8 Antibody) at dilution of 1:1000
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Background
BRD8 is one of the bromodomain-containing proteins, which is an acetylated lysine- binding domain and thought to be involved in regulation of protein acetylation and/or HAT (histone acetyl transferase) activity [PMID: 12963728]. It is also reported to be an accessory subunit of NuA4 HAT complex (also known as TRRAP/TIP60 complex) through biochemical purification [PMID: 16049979]. In addition, it can bind to thyroid hormone receptor-ß and/or retinoid X receptor, and can act as a coactivator of the nuclear hormone receptor-mediated transcription in reporter assays [PMID: 10517671].
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"