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Beta galactosidase antibody

Cat.#: 108482

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Product Information

  • Product Name
    Beta galactosidase antibody
  • Documents
  • Description
    Beta galactosidase Rabbit Polyclonal antibody. Positive WB detected in SH-SY5Y cells. Positive IF detected in Hela cells. Observed molecular weight by Western-blot: 67 kDa
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    Acid beta galactosidase antibody; Beta galactosidase antibody; EBP antibody; Elastin receptor 1 antibody; ELNR1 antibody; galactosidase antibody; beta 1 antibody; GLB1 antibody; Lactase antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Beta galactosidase recombinant protein (Accession Number: NM_000404). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IF: 1:10-1:100

  • Validations

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:117127(GLB1 antibody) at dilution of 1:400

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:117127(GLB1 antibody) at dilution of 1:400

    Immunofluorescent analysis of Hela cells, using GLB1 antibody Catalog No:117127 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

    Immunofluorescent analysis of Hela cells, using GLB1 antibody Catalog No:117127 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

  • Background
    GLB1(Beta-galactosidase) is also named as ELNR1, Lactase.It cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.This protein is identical to the elastin-binding protein (EBP), a major component of the nonintegrin cell surface receptor complex expressed in fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types.Defects in GLB1 are the cause of GM1-gangliosidosis type 1 (GM1G1) ,GM1-gangliosidosis type 2 (GM1G2),GM1-gangliosidosis type 3 (GM1G3) and mucopolysaccharidosis type 4B (MPS4B).
  • References
    • Werner C, Gensch C, Pöss J, Haendeler J, Böhm M, Laufs U. Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis. Atherosclerosis. 216(1):23-34. 2011.
    • Büchner N, Ale-Agha N, Jakob S. Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes. Experimental gerontology. 48(1):8-16. 2013.
    • Turlo KA, Scapa J, Bagher P. β1-integrin is essential for vasoregulation and smooth muscle survival in vivo. Arteriosclerosis, thrombosis, and vascular biology. 33(10):2325-35. 2013.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"