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Product Name
BCL11B antibody
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Description
BCL11B Rabbit Polyclonal antibody. Positive IF detected in SH-SY5Y cells. Positive IP detected in Jurkat cells. Positive WB detected in Jurkat cells, mouse thymus tissue. Observed molecular weight by Western-blot: 116 kDa
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Tested applications
ELISA, WB, IP, IF
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
B cell CLL/lymphoma 11B antibody; B cell lymphoma/leukemia 11B antibody; BCL11B antibody; COUP TF interacting protein 2 antibody; CTIP 2 antibody; CTIP2 antibody; hRit1 antibody; hRIT1 alpha antibody; RIT1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_022898). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:2000
IF: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:108390(BCL11B antibody) at dilution of 1:300
IP Result of anti-BCL11B (IP:Catalog No:108390, 4ug; Detection:Catalog No:108390 1:500) with Jurkat cells lysate 2800ug.
Immunofluorescent analysis of (-20oc Ethanol) fixed SH-SY5Y cells using Catalog No:108390(BCL11B Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
BCL11B, also named as CTIP2, RIT1, CTIP-2, ZNF856B and hRIT1-alpha, is a tumor-suppressor protein involved in T-cell lymphomas. It may function on the P53-signaling pathway. BCL11B is a key regulator of both differentiation and survival during thymocyte development. It tepress transcription through direct, TFCOUP2-independent binding to a GC-rich response element. This antibody is specific to BCL11B.
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