BCL11B antibody

Cat.#: 108390

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Product Information

  • Product Name
    BCL11B antibody
  • Documents
  • Description
    BCL11B Rabbit Polyclonal antibody. Positive IF detected in SH-SY5Y cells. Positive IP detected in Jurkat cells. Positive WB detected in Jurkat cells, mouse thymus tissue. Observed molecular weight by Western-blot: 116 kDa
  • Tested applications
    ELISA, WB, IP, IF
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    B cell CLL/lymphoma 11B antibody; B cell lymphoma/leukemia 11B antibody; BCL11B antibody; COUP TF interacting protein 2 antibody; CTIP 2 antibody; CTIP2 antibody; hRit1 antibody; hRIT1 alpha antibody; RIT1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_022898). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IP: 1:200-1:2000

    IF: 1:20-1:200

  • Validations

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:108390(BCL11B antibody) at dilution of 1:300

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:108390(BCL11B antibody) at dilution of 1:300

    IP Result of anti-BCL11B (IP:Catalog No:108390, 4ug; Detection:Catalog No:108390 1:500) with Jurkat cells lysate 2800ug.

    IP Result of anti-BCL11B (IP:Catalog No:108390, 4ug; Detection:Catalog No:108390 1:500) with Jurkat cells lysate 2800ug.

    Immunofluorescent analysis of (-20oc Ethanol) fixed SH-SY5Y cells using Catalog No:108390(BCL11B Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of (-20oc Ethanol) fixed SH-SY5Y cells using Catalog No:108390(BCL11B Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    BCL11B, also named as CTIP2, RIT1, CTIP-2, ZNF856B and hRIT1-alpha, is a tumor-suppressor protein involved in T-cell lymphomas. It may function on the P53-signaling pathway. BCL11B is a key regulator of both differentiation and survival during thymocyte development. It tepress transcription through direct, TFCOUP2-independent binding to a GC-rich response element. This antibody is specific to BCL11B.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"