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Product Name
BCHE antibody
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Description
BCHE Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue. Positive IF detected in HeLa cells. Positive WB detected in HeLa cells, HEK-293 cells. Observed molecular weight by Western-blot: 85-90 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human; other species not tested.
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Alternative names
Acylcholine acylhydrolase antibody; BCHE antibody; Butyrylcholine esterase antibody; butyrylcholinesterase antibody; CHE1 antibody; Choline esterase II antibody; Cholinesterase antibody; PseudOCholinesterase antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of BCHE recombinant protein (Accession Number: BC008396). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:108385(BCHE Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:108385(BCHE Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:108385(BCHE Antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of HeLa cells using Catalog No:108385(BCHE Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
BCHE(butyrylcholinesterase) is an enzyme expressed in most human tissues. It may have a greater role in cholinergic transmission than previously surmised, making BChE inhibition an important therapeutic goal in Alzheimer's disease(PMID:11848688). BCHE is also named as CHE1 and belongs to the type-B carboxylesterase/lipase family. This is a glycoprotein with the molecular weight from 68 kDa to 90 kDa.
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