BAP1 antibody

Cat.#: 108419

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Product Information

  • Product Name
    BAP1 antibody
  • Documents
  • Description
    BAP1 Rabbit Polyclonal antibody. Positive WB detected in A2780 cells, human placenta tissue, mouse ovary tissue. Observed molecular weight by Western-blot: 91 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    BAP1 antibody; BRCA1 assOCiated protein 1 antibody; Cerebral protein 6 antibody; DKFZp686N04275 antibody; FLJ35406 antibody; FLJ37180 antibody; HUCEP 13 antibody; hucep 6 antibody; KIAA0272 antibody; UCHL2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of BAP1 recombinant protein (Accession Number: NM_004656). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    A2780 cells were subjected to SDS PAGE followed by western blot with Catalog No:108419(BAP1 antibody) at dilution of 1:300

    A2780 cells were subjected to SDS PAGE followed by western blot with Catalog No:108419(BAP1 antibody) at dilution of 1:300

  • Background
    BRCA1-associated protein-1 (BAP1),also named as KIAA0272, hucep-6, DKFZp686N04275, FLJ35406, FLJ37180, HUCEP-13, is a deubiquitinating enzyme whose function in the control of the cell cycle requires both its deubiquitinating activity and nuclear localization(PMID:22374320). It helps to control cell proliferation by regulating HCFC1 protein levels and by associating with genes involved in the G(1)-S transition)(PMID:19188440). Defects in BAP1 may be a cause of mesothelioma malignant (MESOM)(PMID:21642991) and tumor predisposition syndrome (TPDS)(PMID:21874003). The all BAP1s except those of C. quinquefasciatus have a molecular mass of more than 90 kDa(PMID:22374320).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"