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BAG1S/1M antibody

Cat.#: 106999

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Special Price 239.0 USD

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Product Information

  • Product Name
    BAG1S/1M antibody
  • Documents
  • Description
    BAG1S/1M Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue, human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue. Positive WB detected in mouse brain tissue, Jurkat cells, mouse liver tissue. Observed molecular weight by Western-blot: 46 kDa,33 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_004323). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108408(BAG1S-specific antibody) at dilution of 1:800

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108408(BAG1S-specific antibody) at dilution of 1:800

    Immunohistochemical of paraffin-embedded human testis using Catalog No:108408(BAG1S-specific antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:108408(BAG1S-specific antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:108408(BAG1S-specific antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:108408(BAG1S-specific antibody) at dilution of 1:50 (under 40x lens)

  • Background
    BAG1 have been identified that modulate gene transcription through poorly defined mechanisms. Four isoforms of the BAG1 protein (BAG1S, BAG1, BAG1M and BAG1L) can be produced from a common mRNA by use of alternative translation initiation sites, including a non-canonical CTG codon in one instance. The longest, BAG1L (Mr ~50K), contains a nuclear localization signal (NLS) and resides in the nucleus, whereas BAG1M (Mr ~46K) has an incomplete NLS and distributes mainly in cytosol, unless dragged into the nucleus through interactions with other. Distribution of BAG1S(p33) is not clear yet. This antibody recongizes both BAG1M and BAG1S.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"