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Product Name
ASCC1 antibody
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Description
ASCC1 Rabbit Polyclonal antibody. Positive WB detected in Y79 cells, human ileum tissue. Observed molecular weight by Western-blot: 45.5 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ASC 1 complex subunit p50 antibody; ASC1p50 antibody; ASCC1 antibody; CGI 18 antibody; RP11 150D20.4 antibody; Trip4 complex subunit p50 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ASCC1 recombinant protein (Accession Number: NM_001369093). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:108218(ASCC1 Antibody) at dilution of 1:600
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Background
ASCC1 (also known as p50) is a subunit of an uncharacterized complex, the activating signal co-integrator complex (ASCC). ASCC1 has been reported as regulator fo NF-kB pathway and potently inhibits the expression of NF-kB target genes. Mutations in ASCC1 in patients with Barrett esophagus (BE) have been identified as a risk factor of esophageal adenocarcinoma (EAC).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"