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Product Name
ARMC8 antibody
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Description
ARMC8 Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, HeLa cells, HepG2 cells, mouse skeletal muscle tissue. Positive IF detected in MCF-7 cells. Observed molecular weight by Western-blot: 75.5kd
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Tested applications
ELISA, WB, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
armadillo repeat containing 8 antibody; ARMC8 antibody; HSPC056 antibody; S863 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ARMC8 recombinant protein (Accession Number: NM_213654). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IF: 1:10-1:100
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Validations
MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:108152(ARMC8 antibody) at dilution of 1:400
Immunofluorescent analysis of MCF-7 cells using Catalog No:108152(ARMC8 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
Armadillo repeat-containing protein 8 (Armc8) is a key factor to regulate cell membrane adhesion complex through promoting α-catenin degradation. Armc8 expression was elevated during atypia-to-carcinoma progression and may be associated with cancer development of breast carcinoma (PMID: 25119601).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"