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Product Name
APLP1 antibody
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Description
APLP1 Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in mouse brain tissue. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 72 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
Amyloid like protein 1 antibody; APLP antibody; APLP 1 antibody; APLP1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of APLP1 recombinant protein (Accession Number: NM_005166). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108020(APLP1 Antibody) at dilution of 1:1000
IP Result of anti-APLP1 (IP:Catalog No:108020, 4ug; Detection:Catalog No:108020 1:600) with mouse brain tissue lysate 3440ug.
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108020(APLP1 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:108020(APLP1 Antibody) at dilution of 1:50 (under 40x lens)
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Background
APLP1 represents amyloid beta (A4) precursor-like protein 1
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References
- Kuhn PH, Koroniak K, Hogl S. Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons. The EMBO journal. 31(14):3157-68. 2012.
- Dislich B, Wohlrab F, Bachhuber T. Label-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects β-Site APP Cleaving Enzyme (BACE1) Protease Substrates In Vivo. Molecular & cellular proteomics : MCP. 14(10):2550-63. 2015.
- Collins MA, An J, Hood BL, Conrads TP, Bowser RP. Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis. Journal of proteome research. 14(11):4486-501. 2015.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"