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Product Name
Anti-TXNRD2 (3F2) Mouse antibody
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Description
TXNRD2 (3F2) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human
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Alternative names
mitochondrial;selenoprotein Z;SELZ;Thioredoxin reductase 2;Thioredoxin reductase 2 mitochondrial;thioredoxin reductase 3;thioredoxin reductase beta;Thioredoxin reductase TR3;TR 3;TR;TR beta;TR-beta;TRXR 2;TRXR2;TRXR2_HUMAN;TXNRD 2;Txnrd2. antibody
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Isotype
Mouse IgG1
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Preparation
Antigen: Purified recombinant human TXNRD2 protein fragments expressed in E.coli.
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Clonality
Monoclonal
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Formulation
PBS(pH 7.4)containing with 0.02% NaN3 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Western blot detection of TXNRD2 in A431,U251,U2OS,Lncap and Hela cell lysates and using TXNRD2 mouse mAb (1:1000 diluted).Predicted band size: 56KDa.Observed band size: 56KDa.
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Background
Swiss-Prot Acc.Q9NNW7.This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described.
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