Anti-SHP1 (2B7) Mouse antibody

Cat.#: 168266

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Product Information

  • Product Name
    Anti-SHP1 (2B7) Mouse antibody
  • Documents
  • Description
    SHP1 (2B7) Mouse monoclonal antibody
  • Tested applications
    WB, IP
  • Species reactivity
    Human
  • Alternative names
    70 kda SHP1L protein ; 70Z-SHP ; EC 3.1.3.48 ; HCP ; HCPH ; Hematopoietic cell phosphatase ; Hematopoietic cell protein tyrosine phosphatase ; Hematopoietic cell protein-tyrosine phosphatase ; HPTP1C ; Protein tyrosine phosphatase 1C ; Protein tyrosine ph antibody
  • Isotype
    Mouse IgG2a
  • Preparation
    Antigen: Purified recombinant human SHP-1 protein fragments expressed in E.coli.
  • Clonality
    Monoclonal
  • Formulation
    Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of SHP-1 in Human tonsil,Daudi,Jurkat and Raji cell lysates using SHP-1 mouse mAb (1:1000 diluted).Predicted band size:67KDa.Observed band size:67KDa.

    Western blot detection of SHP-1 in Human tonsil,Daudi,Jurkat and Raji cell lysates using SHP-1 mouse mAb (1:1000 diluted).Predicted band size:67KDa.Observed band size:67KDa.

    Immunoprecipitation analysis of Raji cell lysates using SHP-1 mouse mAb.

    Immunoprecipitation analysis of Raji cell lysates using SHP-1 mouse mAb.

  • Background
    Swiss-Prot Acc.P29350.Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"