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Product Name
Anti-RRM1 Rabbit antibody
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Description
RRM1 Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
R1; RR1; RIR1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human RRM1
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/2000-1/10000
IHC: 1/20-1/50
ICC/IF: 1/20-1/100
FC: 1/20-1/100
IP: 1/20-1/50
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Validations
Western blot detection of RRM1 in U2OS,HepG2,MCF7 cell lysates using RRM1 Rabbit mAb(1:500 diluted).Predicted band size:90kDa.Observed band size:90kDa.
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Background
Swiss-Prot Acc.P23921.Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.MiscellaneousTwo distinct regulatory sites have been defined: the specificity site, which controls substrate specificity, and the activity site which regulates overall catalytic activity. A substrate-binding catalytic site, located on M1, is formed only in the presence of the second subunit M2.The level of the enzyme activity is closely correlated with the growth rate of a cell and appears to vary with the cell cycle.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"