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Product Name
Anti-PDZD11/PDZK11 antibody
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Description
Rabbit polyclonal to PDZD11/PDZK11
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Tested applications
ELISA, IHC-P
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Species reactivity
Human PDZD11 / PDZK11
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Alternative names
AI854765 antibody; AIPP1 antibody; PDZD11 antibody; Pdzd11 antibody; PDZK11 antibody; Pdzk11 antibody; PISP antibody; RP13-26D14.3 antibody; RP23-213F21.2 antibody; PISP antibody; AIPP1 antibody; PDZK11 antibody; Pdzk11 antibody; AI854765 antibody; 1810012H22Rik antibody; 2310079D11Rik antibody; 2700099C19Rik antibody; 1810012H22Rik antibody; 2310079D11Rik antibody; 2700099C19Rik antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human PDZD11 / PDZK11 (rh PDZD11 / PDZK11; NP_057568.1; Asp 2-His 140). PDZD11 / PDZK11 specific IgG was purified by Human PDZD11 / PDZK11 affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS with 5% trehalose
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human PDZD11. The detection limit for Human PDZD11 is approximately 0.039 ng/well.
IHC-P: 0.1-1 μg/mL
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Validations
PDZD11 / PDZK11 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Immunochemical staining of human PDZD11 in human appendix with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
PDZD11 / PDZK11 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Immunochemical staining of human PDZD11 in human placenta with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
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Background
PDZ domain-containing protein 11, also known as AIPP1a, PISP, PDZD11 and PDZK11, is a cytosolic protein which contains one PDZ (DHR) domain. PDZD11 bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. PDZD11 is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Full-length human PDZD11 shares 97% amino acids (aa) identity with mouse PDZD11.
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References
- Goellner,G.M. et al., 2003, Ann N Y Acad Sci. 986 :461-71.
- Wolf-Yadlin A., et al., 2007, Proc. Natl. Acad. Sci. USA. 104:5860-5.
- Heibeck T.H., et al.,2009, J. Proteome Res. 8:3852-61.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"