Anti-NGFR antibody

Cat.#: 176719

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Product Information

  • Product Name
    Anti-NGFR antibody
  • Documents
  • Description
    Mouse monoclonal antibody to NGFR
  • Tested applications
    WB, IP, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CD271 antibody; p75NTR antibody; TNFRSF16 antibody; p75(NTR) antibody; Gp80-LNGFR antibody
  • Isotype
    Mouse IgG1
  • Preparation
    This antigen of this antibody was amino acids 393-427 at the c-terminus of ngfr p75 of human origin.
  • Clonality
    Monoclonal
  • Formulation
    Liquid, 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage instructions
    Store at +4℃
  • Applications

    WB: 1:100-1:1,000

    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)

    IF: 1:50-1:500

  • Validations

    Fig1: Westernblot analysis of NGFR p75 expressionin SK-N-NC whole cell lysate.

    Fig1: Westernblot analysis of NGFR p75 expressionin SK-N-NC whole cell lysate.

    Fig2: Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

    Fig2: Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

  • Background
  • References
    • McKay, S.E., et al. 1996. The expression of Trk B and p75 and the role of BDNF in the developing neuromuscular system of the chick embryo. Development 122: 715-724.
    • Hempstead, B.L., et al. 1991. High-affinity NGF binding requires coexpression of the Trk proto-oncogene and the low-affinity NGF receptor. Nature 350: 678-683.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"