Anti-MMP17 antibody

Cat.#: 176570

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Product Information

  • Product Name
    Anti-MMP17 antibody
  • Documents
  • Description
    Rabbit monoclonal antibody to MMP17
  • Tested applications
    ICC, IF, IHC-P, WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    MMP-17 antibody; MT4MMP antibody; MTMMP4 antibody; MT4-MMP antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antigen of this antibody was recombinant protein within human mmp17 aa 1-250.
  • Clonality
    Monoclonal
  • Formulation
    Liquid, 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage instructions
    Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Applications

    ICC: 1:50

    IHC-P: 1:50

    WB: 1:500

  • Validations

    Fig1: ICC staining MMP17 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig1: ICC staining MMP17 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig2: ICC staining MMP17 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig2: ICC staining MMP17 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

    Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-MMP17 antibody. Counter stained with hematoxylin.

    Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-MMP17 antibody. Counter stained with hematoxylin.

  • Background
  • References
    • Puente X S et al. Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res 56:944-949 (1996).
    • Martín-Alonso M et al. Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice. Circ Res 117:e13-26 (2015).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"