Anti-Histone H2B (7E2) Mouse antibody

Cat.#: 168203

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Product Information

  • Product Name
    Anti-Histone H2B (7E2) Mouse antibody
  • Documents
  • Description
    Histone H2B (7E2) Mouse monoclonal antibody
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Synthetic Peptide of Histone H2B
  • Clonality
    Monoclonal
  • Formulation
    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000-3000

    IF: 1/200

  • Validations

    Western blot detection of Histone H2B in Hela and COS7 cell lysates using Histone H2B mouse mAb (1:100000 diluted).Predicted band size:14kDa.Observed band size:14kDa.

    Western blot detection of Histone H2B in Hela and COS7 cell lysates using Histone H2B mouse mAb (1:100000 diluted).Predicted band size:14kDa.Observed band size:14kDa.

    Immunohistochemical analysis of paraffin-embedded human breast caricnoma using Histone H2B uff08uff09Mouse mAb diluted at 1:500.

    Immunohistochemical analysis of paraffin-embedded human breast caricnoma using Histone H2B uff08uff09Mouse mAb diluted at 1:500.

  • Background
    Swiss-Prot Acc.P33778.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"