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Product Name
Anti-GSTK1 antibody
- Documents
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Description
Rabbit polyclonal to GSTK1
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Tested applications
ELISA, WB, IP
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Species reactivity
Human GSTK1
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Alternative names
glutathione S-transferase kappa 1 antibody; GSTK1 antibody; HDCMD47P antibody; GST antibody; GST 13-13 antibody; GST13 antibody; GST13-13 antibody; GSTK1-1 antibody; hGSTK1 antibody; GST class-kappa antibody; glutathione S-transferase k1 antibody; glutathione S-transferase subunit 13 homolog antibody; glutathione S-transferase kappa 1 antibody; Gstk1 antibody; 0610025I19Rik antibody; AW260476 antibody; DsbA-L antibody; GST 13-13 antibody; GST class-kappa antibody; GSTK1-1 antibody; glutathione S-transferase class kappa antibody; glutathione S-transferase subunit 13 antibody; mGSTK1 antibody; GST antibody; GST13 antibody; hGSTK1 antibody; GSTK1-1 antibody; GST13-13 antibody; DsbA-L antibody; AW260476 antibody; 0610025I19Rik antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human GSTK1 (rh GSTK1; Q9Y2Q3-1; Gly2-Leu226). GSTK1 specific IgG was purified by Human GSTK1 affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 2-10 μg/ml
ELISA: 0.1-0.2 μg/ml
This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Human GSTK1.
IP: 0.5-2 μg/mg of lysate
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Validations
GSTK1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
GSTK1 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation
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Background
GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a variety of reactions in both eukaryotes and prokaryotes. They catalyze the conjugation of reduced glutathione with potentially toxic, xenobiotic substrates, thus aiding excretion from the body. GSTK1(glutathione S-transferase kappa 1) is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. GSTK1 functions in cellular detoxification.
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References
- Zhang QH, et al. (2001) Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. Genome Res. 10(10):1546-60.
- Morel F, et al. (2004) Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization. J Biol Chem. 279(16): 16246-53.
- Jowsey IR, et al. (2003) Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase. Biochem J. 373(Pt 2):559-69.
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