Anti-CD226/DNAM-1 antibody

Anti-CD226/DNAM-1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit monoclonal to CD226/DNAM-1

FCM

Mouse CD226 / DNAM-1

dnam-1 antibody; mCG_1042474 antibody; Platelet and T cell activation antigen 1 isoform 3 antibody; CD226 antigen antibody; Pta1 antibody; CD226 antigen antibody

Rabbit IgG

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD226 / DNAM-1 (rM CD226 / DNAM-1; NP_848802.2; Met1-Pro254) and conjugated with PE under optimum conditions, the unreacted PE was removed.

Monoclonal

Aqueous solution containing 0.5% BSA and 0.09% sodium azide

This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

FCM

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.

• Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
• Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
• Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.