AMPK gamma 1 antibody

AMPK gamma 1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

AMPK gamma 1 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue, human skeletal muscle tissue. Positive WB detected in K-562 cells, HeLa cells, Jurkat cells. Observed molecular weight by Western-blot: 35-38 kDa

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

AMPK gamma1 antibody; AMPK subunit gamma 1 antibody; AMPKG antibody; PRKAG1 antibody

Rabbit IgG

This antibody was obtained by immunization of AMPK gamma 1 recombinant protein (Accession Number: NM_002733). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1, synonyms: AMPKG, MGC8666) is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an catalytic subunit, and non-catalytic and subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and -hydroxy-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK.

• Zhu K, Chen X, Liu J, Ye H, Zhu L, Wu JY. AMPK interacts with DSCAM and plays an important role in netrin-1 induced neurite outgrowth. Protein & cell. 4(2):155-61. 2013.