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Product Name
AMMECR1 antibody
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Description
AMMECR1 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, mouse liver tissue, mouse uterus tissue. Positive IHC detected in human cerebellum tissue. Observed molecular weight by Western-blot: 45 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
AMMECR1 antibody; AMMERC1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of AMMECR1 recombinant protein (Accession Number: NM_001025580). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107996(AMMECR1 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human cerebellum tissue slide using Catalog No:107996(AMMECR1 Antibody) at dilution of 1:50 (under 40x lens)
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Background
AMMECR1 also named as AMME syndrome candidate gene 1 protein is a 333 amino acid protein, which contains 1 AMMECER1 domain. Containing a glycine-rich N terminus, the AMMECR1 protein exhibits putative nuclear localization and a substantial level of instability, suggesting it plays a role in regulation. The deletion of AMMECR1 gene may be involved in glomerulonephritis, sensorineural hearing loss, mental retardation, midface hypoplasia and elliptocytosis.
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