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Alpha galactosidase A antibody

Cat.#: 107870

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Special Price 239.0 USD

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Product Information

  • Product Name
    Alpha galactosidase A antibody
  • Documents
  • Description
    Alpha galactosidase A Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue, human liver cancer tissue, mouse liver tissue. Positive WB detected in HeLa cells, HEK-293 cells. Positive IP detected in HEK-293 cells. Observed molecular weight by Western-blot: 49 kDa
  • Tested applications
    ELISA, IHC, IP, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Alpha galactosidase A antibody; galactosidase antibody; alpha antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Alpha galactosidase A recombinant protein (Accession Number: NM_000169). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107870(GLA antibody) at dilution of 1:1000

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107870(GLA antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human liver using Catalog No:107870(GLA antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:107870(GLA antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:107870(GLA antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:107870(GLA antibody) at dilution of 1:50 (under 40x lens)

    IP Result of anti-GLA (IP:Catalog No:107870, 3ug; Detection:Catalog No:107870 1:1000) with HEK-293 cells lysate 1800ug.

    IP Result of anti-GLA (IP:Catalog No:107870, 3ug; Detection:Catalog No:107870 1:1000) with HEK-293 cells lysate 1800ug.

  • Background
    GLA, also named as Melibiase, Agalsidas and Alpha-galactosidase A, Belongs to the glycosyl hydrolase 27 family. It hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. Fabry disease is an X-linked lysosomal storage disorder resulting from the deficient activity of GLA. Enzyme replacement therapy (ERT) with GLA is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"