-
Product Name
AFMID antibody
- Documents
-
Description
AFMID Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue. Positive WB detected in mouse liver tissue, human liver tissue. Observed molecular weight by Western-blot: 30kd
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
AFMID antibody; arylformamidase antibody; DKFZp686F03259 antibody; Kynurenine formamidase antibody; Probable arylformamidase antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_001145526). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:107911(AFMID antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:107911(AFMID Antibody) at dilution of 1:50(under 10x lens)
Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:107911(AFMID Antibody) at dilution of 1:50(under 40x lens)
-
Background
AFMID,also named as KF, belongs to the AFMID family. AFMID catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the conversion of tryptophan to nicotinic acid, NAD(H) and NADP(H). AFMID is required for elimination of toxic metabolites.
-
References
- Tummala KS, Gomes AL, Yilmaz M. Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage. Cancer cell. 26(6):826-39. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"