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Product Name
ADARB1 antibody
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Description
ADARB1 Rabbit Polyclonal antibody. Positive WB detected in rat brain tissue, A431 cells. Positive IP detected in A431 cells. Observed molecular weight by Western-blot: 70 kDa,80 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Rat; other species not tested.
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Alternative names
ADAR2 antibody; ADAR2a antibody; ADAR2a L1 antibody; ADAR2a L2 antibody; ADAR2a L3 antibody; ADAR2b antibody; ADAR2c antibody; ADAR2d antibody; ADAR2g antibody; ADARB1 antibody; DRABA2 antibody; DRADA2 antibody; dsRNA adenosine deaminase antibody; RED1 antibody; RNA editing deaminase 1 antibody; RNA editing enzyme 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ADARB1 recombinant protein (Accession Number: NM_001112). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
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Validations
rat brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:107775(ADARB1 antibody) at dilution of 1:1000
IP Result of anti-ADARB1 (IP:Catalog No:107775, 4ug; Detection:Catalog No:107775 1:1000) with A431 cells lysate 1200ug.
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Background
ADARB1(Double-stranded RNA-specific editase 1) is also named as ADAR2, DRADA2, RED1 and belongs to the ADAR family. It catalyses the deamination of adenosine to inosine at the GluR2 Q/R site in the pre-mRNA encoding the critical subunit of AMPA receptors. This protein has 5 isoforms with the molecular weight from 77 kDa to 81 kDa and 7 kDa, but it can be detected a very strong band at 50 kDa in addition to a predicted band at 75 kDa as the result of western blot, while ADARB1 has several alternative splice variants(PMID:23103828).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"