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Product Name
ADAM19 antibody
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Description
ADAM19 Rabbit Polyclonal antibody. Positive WB detected in NIH/3T3 cells. Positive IP detected in NIH/3T3 cells. Observed molecular weight by Western-blot: 70 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
ADAM 19 antibody; ADAM19 antibody; FKSG34 antibody; MADDAM antibody; Meltrin beta antibody; MLTNB antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ADAM19 recombinant protein (Accession Number: BC024214). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
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Validations
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107764(ADAM19 Antibody) at dilution of 1:300
IP Result of anti-ADAM19 (IP:Catalog No:107764, 4ug; Detection:Catalog No:107764 1:300) with NIH/3T3 cells lysate 1200ug.
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Background
Meltrinβ(ADAM19) is a metalloprotease-disintegrin expressed in the peripheral nervous system and other organs during embryogenesis. Its specific patterns of expression during embryogenesis suggest that it is involved in the development of the peripheral nervous system, skeletal muscle, bone and heart tissue(PMID:12482604). It participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell.
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