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Product Name
ACE2 antibody
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Description
ACE2 Rabbit Polyclonal antibody. Positive IP detected in mouse kidney tissue. Positive WB detected in mouse kidney tissue, human skeletal muscle tissue. Observed molecular weight by Western-blot: 90-110 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ACE related carboxypeptidase antibody; ACE2 antibody; ACEH antibody; Angiotensin converting enzyme 2 antibody; DKFZp434A014 antibody; Metalloprotease MPROT15 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ACE2 recombinant protein (Accession Number: NM_021804). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IP: 1:500-1:5000
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Validations
mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:107736(ACE2 antibody) at dilution of 1:1000
IP Result of anti-ACE2 (IP:Catalog No:107736, 5ug; Detection:Catalog No:107736 1:1000) with mouse kidney tissue lysate 4000ug.
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Background
ACE2 contains a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It is the only known mammalian homologue of the zinc-metallopeptidase angiotensin-converting enzyme (ACE), a critical regulator of the reninangiotensin system.ACE2 has a more restricted tissue distribution than ACE, being found predominantly in the heart, kidneys, and testes although low levels have been detected in a variety of tissues(PMID:15983030). It can be N-Deglycosylation(PMID:16166094).It has 2 isoforms produced by alternative splicing.This antibody is specific to ACE2.
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