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Product Name
AADACL1 antibody
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Description
AADACL1 Rabbit Polyclonal antibody. Positive IP detected in COLO 320 cells. Positive WB detected in COLO 320 cells. Positive IHC detected in human brain tissue, human kidney tissue, human lung tissue, human ovary tissue, human skin tissue, human spleen tissue. Observed molecular weight by Western-blot: 55 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
AADACL1 antibody; KIAA1363 antibody; KIAA1363 antibody; NCEH1 antibody; NCEH antibody; NCEH antibody; NCEH1 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of AADACL1 recombinant protein (Accession Number: NM_001005476). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
COLO 320 cells were subjected to SDS PAGE followed by western blot with Catalog No:107670(AADACL1 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human brain using Catalog No:107670(AADACL1 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human brain using Catalog No:107670(AADACL1 antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-AADACL1 (IP:Catalog No:107670, 4ug; Detection:Catalog No:107670 1:500) with COLO 320 cells lysate 400ug.
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Background
AADACL1(Arylacetamide deacetylase-like 1) is also named as NCEH1, KIAA1363 and belongs to the 'GDXG' lipolytic enzyme family. The transmembrane enzyme, AADACL1, controls the production of the monoalkylglycerol ether (MAGE) class of NELs in cancer cells and acts as a 2-acetyl MAGE hydrolase and is likely the principal source for this activity in tumor cells(PMID:21513884). The full length protein has three glycosylation sites and can be N-glycosylated(PMID:19159218). It has 3 isoforms produced by alternative splicing.
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